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NUTRITION INGREDIENTS

β-Nicotinamide Mononucleotide NMN
CAS 1094-61-7

Product Name β-Nicotinamide Mononucleotide
Other Name β-Nicotinamide Mononucleotide NMN、Nicotinamide nucleotide、3-Carbamoyl-1-[5-O-(hydroxyphosphinato)-β-D-ribofuranosyl]-pyridinium
CAS No. 1094-61-7
Purity 99%
Bulk Density Powder: 0.3-0.7 g/ml, Granular: 0.6-0.9 g/ml
EINECS NO. 214-136-5
Molecular Formula C₁₁H₁₅N₂O₈P
Molecular Weight 334.22
Appearance Odorless, white to slightly yellow crystalline powder
Packing 1kg/5kg Aluminum foil bag, 25kg/Drum, 25kg/Carton, or customized as per customer's requirements
Storage Store in a cool, dry place, tightly sealed, away from heat and light
MOQ 1 KG
Payment T/T, LC or DA
Delivery Time Ready Stock in Local Warehouse, 1-3 days
Origin China
Shipping DHL, FedEx, TNT, EMS, By Sea, By Air

Description

  

β-Nicotinamide Mononucleotide (β-NMN) is the direct precursor of core coenzyme NAD⁺ in the human body, which is called “Cell Energy Fuel” in the health and wellness sector and anti-aging sector. When you oral intake it, it can penetrate the cell membrane quickly and transform NAD⁺, triggering sirtuins and repairing damaged DNA and reversing mitochondrial aging.

   

Applications

 

1.In the field of anti-aging and advanced dietary supplements, it triggers mitochondria to produce ATP by improving NAD⁺ levels in the human body. The main function is to relieve chronic fatigue, boost muscular endurance, and restore physical functions comprehensively. What’s more, it helps repair enzymes (such as PARP) to restore the damaged DNA chain and active seven sirtuins, slowing down biological aging and reversing chronic organ senescence in terms of genes.

  

2.In brain health, cognitive support and “brain fog”sectors, it can optimize energy metabolism of brain neurons and inhibit low-grade brain inflammation, so it is used to develop premium brain health supplements that helps improve memory and concentration and relieve long-term mental fatigue. Clinical research indicated that  improving NAD⁺ levels can prevent neurons from oxidative damage, and NAD⁺ is the key active ingredient to delay brain aging and protect against Alzheimer's in compound formulations.

  

3.In functional skincare and premium aesthetics sectors, topical β-Nicotinamide Mononucleotide (β-NMN) penetrates down to the basal layer of epidermal cells, inhibiting melanin deposition and collagen degradation caused by UV. Therefore, as a star ingredient, it is added to luxury anti-age night creams, anti-wrinkle eye creams and firming priming serums. Besides, it boosts basal cell metabolism and accurately repairs barriers. 

   

Specifications

  
General Information
Product Name β-Nicotinamide Mononucleotide
Processing Method Enzymatic Reaction
Formula C₁₁H₁₅N₂O₈P
CAS No. 1094-61-7
  
Item Specification Result Method
Physical and Chemical Property
Appearance White Powder Conforms Visual
Moisture content ≤1.0 g/100g 0.30 g/100g Karl-Fischer method
Bulk Density 0.3-0.7 g/mL 0.61 g/mL Average Bulk Density
Identification Consistent with the control map Conforms IR
pH 2.5-4.5 4.06 pH meter
Purity ≥99.9% 99.95% HPLC
Content ≥99.9% 101.12% HPLC
Residue Analysis
Ethanol Solvent Residue ≤1000 mg/kg Conforms GC
Lead (Pb) ≤0.10 mg/kg Conforms ICP-MS
Arsenic (As) ≤0.10 mg/kg Conforms ICP-MS
Cadmium (Cd) ≤0.10 mg/kg Conforms ICP-MS
Mercury (Hg) ≤0.10 mg/kg Conforms ICP-MS
Microbiological Tests
Total Plate Count ≤500 cfu/g Conforms AOAC 990.12
Total Yeast & Mold ≤50 cfu/g Conforms AOAC 997.02
E. coli Negative/25g Conforms AOAC
Salmonella Negative/25g Conforms AOAC
S. aureus Negative/25g Conforms AOAC 2003.07

      

Advantages

 

1.Through adopting the full enzymatic catalysis process (fully mimic the in vivo synthetic pathway), our products’ purity remains at ≥99% that is the highest standard in the whole industry. In addition, we ensure that non-active α-NMN shows a zero detection rate, and we also provide detailed optical isomers HPLC chromatogram with each batch.

  

2. Our upstream recrystallization process can produce high-density and uniform crystalline powder via powder engineering optimization.

  

3.The purification and catalysis processes rely only on purified water and bio-enzyme catalysts without any hazardous chemical solvents in production lines.

  

4.We provide certificates that comply with the highest international standards, such as COA, MSDS and TDS. Besides, we also strictly control the heavy metals (such as Lead, Arsenic, Mercury and Cadmium) microorganisms, and aflatoxins that exceed the standard of EFSA. In conclusion, we provide perfect documents for clients!

      

FAQ

 

Q1: What’s the purity of NMN? And how do we ensure the product doesn’t contain ineffective α-NMN?

A: The purity of β-Nicotinamide Mononucleotide (β-NMN) crystalline powder is ≥ 99% as determined by HPLC. NMN has two optical isomers that include  α-configuration and β-configuration. Scientific research confirms that only β-Nicotinamide Mononucleotide (β-NMN) possesses bioactivity and safely converts into NAD⁺ ; by contrast, α-NMN doesn’t have any anti-aging effects, and carriers potential metabolic risk in the human body. Besides, we also adopt the full enzymatic catalysis process to ensure non-active α-NMN shows a zero detection rate at the source. At the same time, we also provide you with detailed optical isomers HPLC chromatogram with each batch, ensuring you can receive the finest anti-aging products.

  

Q2: Because the highly automated OEM or ODM has strict requirements for flowability of antibody ingredients, what’s your powder index of NMN?

A: By the recrystallization process to optimize powder engineering, we can provide crystalline powder with high bulk density (Bulk Density is controlled between 0.5 to 0.7g/ml) and uniformity.

  

Q3: What does apply process to produce β-Nicotinamide Mononucleotide (β-NMN)? Does it have toxic organic solvent or heavy metal residues?

A: The purification and catalysis processes rely only on purified water and bio-enzyme catalysts without any hazardous chemical solvents in production lines. When tested by authoritative third-party organizations (such as SGS or Eurofins), the products show zero chloroform residues and behave perfectly in the Ames Test and Acute Toxicity Test. It remains safe even with long-term high-dose oral administration or topical application in advanced aesthetic medical treatments.

  

Q4: Why is the combination of β-Nicotinamide Mononucleotide (β-NMN) and apigenin widely recognized within the scientific community as the “Ultimate NAD⁺ Boost Complex”?

A: NMN is responsible for “Revenue Growth”:β-Nicotinamide Mononucleotide (β-NMN), as a direct precursor, when you oral intake it, it can penetrate the cell membrane quickly and transform NAD⁺, thereby charging for mitochondria.  Apigenin is responsible for “Cost Control” : With aging, CD38 is increasing and consuming NAD⁺ rapidly. However, apigenin is called the most potent inhibitor of CD38 that prevents CD38 from taking NAD⁺, while making NMN convert into NAD⁺, thereby helping NAD⁺ be stored in the cells.

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