Amygdalin
CAS 29883-15-6

Applications

1.In the pharmaceutical industry, amygdalin, a classic natural botanical medicine ingredient, is the core raw material of various prescription and proprietary Chinese medicines for relieving cough and asthma.

2. Within functional skincare and topical beauty sectors, amygdalin delivers potent anti inflammatory activity: it lowers the expression of cutaneous inflammatory factors via modulating inflammatory signalling pathways, making it well suited for high grade creams and lotions formulated to ease sensitive skin redness and swelling, repair acne marks and soothe sundamaged skin post exposure. In addition, certain metabolites produced by the hydrolysis of amygdalin help promote subcutaneous microcirculation and accelerate skin metabolism. Thanks to their natural antioxidant properties, these metabolites are incorporated into overnight repair formulations by leading cosmeceutical brands to lift facial dullness, fade pigment spots and even out uneven skin tone.

Specifications

Advantages

1.Applying multistage recrystallization and precision chromatographic separation techniques, we consistently supply amygdalin crystalline powder 99% purity. Its appearance shows a pure white to off-white crystalline powder with the help of this process, resulting in crystal clear solutions and no crystal precipitation and no suspended matter when amygdalin is dissolved in water. 

2.Throughout production, we rigorously limit non-specific plant impurities and strip residual free highly toxic constituents left from upstream crude extraction, ensuring that the raw material complies with strict safety benchmarks for pharmaceutical and premium topical cosmetics while allowing full, consistent pharmacological activity.

3.We guarantee our raw material originates entirely from premium, mold-free natural bitter almond kernels (seeds), free of mould. We leverage our factory’s well-established non-destructive all-physical continuous countercurrent extraction process to deliver high-yield separation whilst preserving intact glycosidic bond structures, enabling us not only to guarantee premium purity of 99%, but also to offer keenly competitive prices across global markets.

4.In terms of aflatoxins, PAHs and microbial limits, as well as heavy metal standards of lead, arsenic, mercury and cadmium, our amygdalin complies with the official specification limits set by the EU and US FDA.

5.We are fully able to supply a compliant Non-Dangerous Goods Identification Certificate; whether for 1kg research-grade samples or tonne-sized commercial bulk shipments, we guarantee seamless customs clearance and direct delivery to clients’ overseas facilities.

FAQ

Q1: Is your Amygdalin naturally extracted? And what is purity?

A: Yes, it is a natural extract. Our amygdalin is sourced exclusively from seeds of Prunus armeniaca L., a Chinese native species belonging to the Rosaceae. Applying advanced multistage recrystallization and specific adsorption purification techniques, we consistently supply amygdalin crystalline powder 99% purity, the powder ranges from pure white to off-white, dissolves completely to form clear aqueous solutions and contains no residual non-target botanical impurities.  

Q2: Amygdalin belongs to cyanogenic glycosides, but how do you ensure the safety of the product in the application or research and development of skincare products?

A: Safety and quality are our baseline standards. By refining our manufacturing workflows, we rigorously restrict free highly toxic constituents and sensitizing quinone-based impurities at the high-purity crystallisation phase. Thanks to the outstanding structural stability of 99% pure amygdalin monomer, uncontrolled hydrolysis rarely takes place in topical skincare formulations or lab R&D work when used within permitted dosage limits and standard formulation environments, excluding strong acids, strong alkalis or external β-glucosidase; the ingredient delivers excellent safety with minimal formulation irritation.

Q3: Some overseas buyers refer to amygdalin as "vitamin B17" or Laetrile, may we legally use these two denominations in our product labelling and marketing claims?

A: Though widely known as "Vitamin B17" or Laetrile in civil-use and certain niche health sectors, leading global regulators such as the US FDA and EU EFSA have formally confirmed that amygdalin is not categorised as a vitamin under biological classification.Therefore, we recommend labelling the product either as a traditional Chinese herbal extract or by its official generic chemical name, Amygdalin. We strongly advise against any unsubstantiated medicinal claims such as anti-cancer or cancer prevention on finished packaging to keep your brand fully compliant with local market regulations.

Q4: What are the core efficacy and mechanism of Amygdalin in external functional skincare products?

A: Pharmacological research shows that It can markedly down regulate subcutaneous inflammatory factor expression and delivers outstanding soothing benefits for sensitive skin redness and swelling, acne scar recovery and post sun damage. In addition, it can also gently promote the microcirculation of local skin and accelerate melanin metabolism. What’s more, with inherent free-radical scavenging properties, amygdalin works well in premium overnight repair creams and brightening serums to even skin tone and restore a translucent complexion.