Puerarin
CAS 3681-99-0

Applications

1.In dietary supplements and the global health and wellness industry, puerarin acts a “natural vasodilator” , helping dilate coronary and cerebral blood vessels, reduce vascular resistance and improve microcirculation. As a result, it is widely used in the production of compound dietary supplements for cardiac care, blood pressure regulation and improved cerebral perfusion. Meanwhile, as a natural C-glycosidic isoflavone compound, puerarin enables bidirectional regulation of endogenous oestrogen levels in the human body. It is therefore extensively processed into capsules and tablets targeting anti-ageing, relief of menopausal symptoms and endocrine regulation. In addition, puerarin hinders alcohol absorption, accelerates acetaldehyde breakdown within the human body and mitigates alcoholic liver injury. Accordingly, puerarin is a key raw material for high-grade hangover relief preparations, sobering beverages and liver-protection tablets.

2.In functional skincare and premium cosmeceutical market, puerarin is the popular ingredient in anti-early-aging serums and creams with rigorous antiglycation activity, inhibiting AGEs formation and preventing skin sagging and dullness induced by collagen yellowing and embrittlement. Besides, puerarin inhibits tyrosinase activity within melanocytes via specific competitive binding, curbing melanin production at the source, hence it displays obvious pharmacological efficacy in fading pigmentation and brightening skin tone. With its excellent capacity to improve microcirculation, it exerts soothing and anti inflammatory effects to alleviate facial telangiectasia (such as telangiectasia,seasonal allergic flushing). 

3.In the conventional pharmaceutical and API (Active Pharmaceutical Ingredient) and pharmaceutical intermediate field, puerarin (such as puerarin injection) is widely used to treat coronary heart disease (CHD), angina pectoris, myocardial infarction (MI) and sudden sensorineural hearing loss (SSNHL) and other diseases. Global research and development institutions for generic drugs and natural medicines maintain steady demand for high purity pharmaceutical grade puerarin.

Specification 

Advantages

1.We always provide monomeric puerarin with the purity of ≥98% via a selective macroporous resin adsorption process and multi-stage recrystallisation purification process. Its appearance shows a pure white to off-white crystalline powder, and it shows excellent clarity with no impurities or foreign odour after dissolution in water.

2. At the upstream of the production line, we adopt fully automated continuous countercurrent extraction technology and only employ purified water and ethanol for extraction. Most importantly, we ensure no toxic chlorinated hydrocarbon or ester-based organic solvents are incorporated into our products, enabling globally competitive pricing alongside zero detectable residual toxic solvents.

3. It complies with and is even stricter than the access limit standards of the European Food Safety Authority (EFSA) and the US Food and Drug Administration (FDA) that established the control standards of the residue of aflatoxin, polycyclic aromatic hydrocarbon (PAHs), sulfur dioxide, microbial limit and the others.

4. We offer complete COA, MSDS, and TDS. Moreover, in response to audit demand from overseas well-known brand clients, we coordinate with internationally authoritative third-party institutions, such as SGS or Eurofins, to provide independent test reports.

FAQ

Q1: What is the purity of your puerarin? And what is the specification?

A: The purity of the puerarin monomeric crystalline powder is at ≥98% (HPLC test) with the appearance of a pure white to off-white and no plant pigments. It has been purified from multilevel recrystallization, which completely removes associated impurities, such as daidzein, an ineffective isoflavone. When dissolved in water, the resulting solution is perfectly clear, free from suspended matter and foreign odour. It is an optimal raw material specially developed for high-grade health supplements, cosmeceutical formulations and pharmaceutical intermediates.

Q2: Radix puerariae comes in two varieties: pueraria montana and pueraria thomsonii. Which one is your puerarin derived from? And what are the differences between pueraria montana and pueraria thomsonii?

A: Most cheap radix puerariae on the market are derived from pueraria thomsonii. The main component of pueraria thomsonii is starch, and the content of puerarin is very low. In contrast, pueraria montana is naturally rich in high concentrations of puerarin and other active isoflavones compounds. Exclusively, we use superior pueraria montana as raw materials, which is not only ensured that our product has stronger and purer pharmacological activity, but also offers competitive cost and pricing advantages from the source.

Q3: What role does puerarin play in women’s health management and weight or metabolic regulation?

A: Puerarin is a naturally occurring isoflavone boasting prominent bidirectional oestrogenlike biological activity. It effectively alleviates hot flushes, osteoporosis and endocrine irregularities triggered by menstruation and the menopausal transition, with no associated adverse effects. Furthermore, the ingredient dilates coronary vessels and enhances cerebral perfusion, rendering it well suited for cardiac care and blood pressure regulation in middleaged and older adults. Furthermore, it can accelerates acetaldehyde metabolism, serving as a core ingredient in premium natural hangover disappear, lliver - protection capsules, and functional beverages.

Q4: What kind of caffeine do you use to extract in the puerarin production process? Does the product meet the standards of European and American for pesticide residues and heavy metals?

A: We use only purified water and edible alcohol as solvents in our entire extraction, separation, and purification process, where we never use toxic or harmful chlorinated hydrocarbons or ester organic solvents, and solvent residue levels are far below the strictest international limits. Because of our strict control over upstream harvesting sites, our puerarin complies with the maximum limits set by the European Food Safety Authority (EFSA) and the US FDA (such as California Proposition 65) for heavy metals (lead, arsenic, mercury, cadmium), sulfur dioxide residues, polycyclic aromatic hydrocarbons (PAHs), and microbial limits, which even in some cases exceeds. So, it provides you with solid assurance of compliance.