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NUTRITION INGREDIENTS

Urolithin A
CAS No. 1143-70-0

Product Name Urolithin A
CAS No. 1143-70-0
EINECS No. 1592732-453-0
Molecular Formula C₁₃H₈O₄
Molecular Weight 228.2
Appearance Off-white to yellow powder
Packing 1kg/5kg Aluminum foil bag
25kg/Drum
25kg/Carton
or as per customer's requirement
Storage Store in a cool, dry place, tightly sealed, away from heat and light
MOQ 1KG
Payment T/T, LC or DA
Delivery Time Ready Stock in Local Warehouse, 1-3 days
Origin China
Shipping DHL, FedEx, TNT, EMS, By Sea, By Air

Description

  

Urolithin A (UA) is not directly existed in the foods, rather a postbiotic. It is a highly active and natural metabolite produced from Ellagitannins that it is existed in kinds of foods such as pomegranates and berries and so on are metabolized by intestinal flora. What’s more, Urolithin A (UA) has become the scientific of consensus and uncommon throughout materials by stimulating the mitophagy to achieve cellular anti-aging.

   

Applications

  

1. Triggers Mitophagy: As age goes on, the poor mitochondrion existed in cells will be accumulated, resulting in a decline in energy levels. Urolithin A seems to be a “cleaner” in cells that it can accurately identify and remove functional disorder aged mitochondria, and promote the regeneration of mitochondrial health .

   

2. Revitalizes Muscle Health: The clinical research shows that Urolithin A can significantly promote muscle strength and endurance. For senior citizens aged 40+, it is the top raw material for preventing muscle loss (Sarcopenia).

    

3. Cellular Anti-Aging: Urolithin A can originally improve cellular energy level (ATP) through optimizing mitochondrial health , and then help your body deal with chronic inflammation and a reduction in metabolic energy due to senescence.

   

4. Neuroprotection: The latest study indicates that Urolithin A is able to cross blood-brain barrier (BBB) and has a preventive effect on neurodegenerative diseases (NDDs).

    

Specifications

       
tem Specification Test Method
Active Ingredient
Purity NLT 98.0% HPLC
Physical Control
Appearance Off-white to yellow powder Visual
Identification The spectrum corresponds to reference HNMR
Water Content NMT 1.0% Karl Fischer
Residue Solvents Methanol: NMT 3000ppm GC
Bulk Density 0.25g/cm³ USP-NF 2024
Chemical Control
Heavy metals NMT 1ppm ICP-MS
Arsenic (As) NMT 1ppm ICP-MS
Cadmium (Cd) NMT 1ppm ICP-MS
Lead (Pb) NMT 1ppm ICP-MS
Mercury (Hg) NMT 0.1ppm ICP-MS
Microbiological Control
Total Plate Count NMT 1000cfu/g USP-NF 2024
Yeast & Mold NMT 100cfu/g USP-NF 2024
Salmonella Negative USP-NF 2024
E. Coli Negative USP-NF 2024
Staphylococcus Aureus Negative USP-NF 2024
Packing and Storage
Storage Store at room temperature in a well-closed container away from moisture and direct sunlight.
Shelf Life 2 years if sealed and stored properly.
    

Advantages

 

We deeply know that trust is worth more than price in the nutrition market. Therefore, the Urolithin A supplied by us possesses core competitive advantages:

  
1.Premium Purity & Stability:

Standard of specifications: The purity of Urolithin A is stably maintain 98% and above (testing by HPLC).
Control impurity: We always utilize the advanced synthesis technology and strictly control residual solvents and heavy metal index, which significantly exceeds the industry standard. In short, it means your terminal products have a long shelf life and stable physical characteristics.

  
2.Rigorous Compliance & Documentation

A complete set of technical documents: We are able to provide complete COA (Certificate of Analysis), MSDS (Material Safety Data Sheet) and TDS (Technical Data Sheet).
Traceability system: Original production records are available for each batch of products. Not only are we selling products, but we also provide “certainty”, ensuring your brands can pass the random test from customs and third-party testing institutions. 

  
3.Flexible Formulation Solutions:

Diversity of specifications: Depending on the different applications, we will provide high flowability powders (suitable for capsule filling) and ultra-fine powder (suitable for functional beverages, and enhancing bioavailability). 
Suggestions of formulations: Based on insights of the global market, we can provide recommendations for collaborative formulations (such as UA + NM or UA + Coenzyme Q10) to help you break into new markets in a short space of time.

  
We are not just your supplier, we are your partner in overseas markets.We have a well-established integrated system of logistics in Shandong province that enables quick response and safe delivery in the range of global markets and ensures your production lines don’t come to a standstill due to material shortages.

      

FAQ

 

Q1: Is Urolithin A extracted directly from pomegranates?
A: No. Although pomegranates have a lot of Ellagitannins, Urolithin A is not directly extracted from its. Actually, Urolithin A is a production of metabolites by intestinal flora. Approximately 30% to 40% of the global populations possess the specific intestinal flora that transforms a large of Urolithin A, so it is the only reliable way that ensures you achieve an effect of anti-aging by directly supplying high purity synthetic Urolithin A.

  

Q2: what’s the core function of Urolithin A?
A: It mainly triggers mitophagy. As age progresses, the poor mitochondria existed in cells will not be cleaned, resulting in a decline in metabolic efficiency. Urolithin A can accurately identify and promote your body to remove “cellular debris” and then promote the regeneration of mitochondrial health. This function system receives numerous bibliographic supports from the top journal《Nature Medicine》.

  

Q3:Why the specification of Urolithin A is 98%+?
A: As a kind of materials in fine chemical, the safety and bioactivity of products are decided by its purity. The lower purity materials may contain un-reacted intermediates or residual solvent. Therefore, we always persist the HPLC purity standard of 98% and above to ensure clients gain high consistency in formulations, and prevent any discoloration or odour issues in the terminal products.

   

Q4: With which ingredients does Urolithin A produce a synergy?
A: Urolithin A is an omnipotent player in anti-aging formulations.
The aspect of anti-aging: We suggest that Urolithin A is combined with NMN or NR to improve level of NAD+ and repair mitochondria achieving dual anti-senescence.
The aspect of performance nutrition: We suggest that Urolithin A is combined with Creatine and Branched-Chain Amino Acid (BCAA) to increase muscle mass whilst enhancing muscle break-out force and endurance through Urolithin A.

  

Q5: How is the compliance and safety of Urolithin A?
A: Urolithin A has been granted GRAS (Generally Recognized as Safe) status by the US FDA. The materials supplied by us strictly obey the Quality Management System (QMS), and additionally each batch is accompanied by a complete Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS). Whether you are exporting to North America, Europe or Southeast Asia, our technical documentation provides robust support for your product registration.

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