Asiaticoside
CAS16830-15-2

Applications

1.In functional skincare and premium cosmeceutical market, it inhibits inflammatory cytokines and alleviates erythema, skin pyrexia and stinging sensation, which is widely used in mesotherapy formulations, post-laser repair creams, medical facial dressings and anti-redness serums tailored for sensitive skin. Besides, it is one of the extremely rare plant-derived monomers that triggers fibroblasts and penetrates deep into the dermis to boost endogenous the synthesis of type I and type III collagen. Because it can rebuild reticular layer of dermis, it is widely used in premium anti-ageing, wrinkle-reducing and firming eye creams and facial creams. In addition, it accelerates epidermal cell migration to promote the synthesis of neovascularisation, helping repair damaged atrophic acne pits and fade fresh red post-acne erythema. 

2.Within the market for scar remodeling and intensive care ointments, asiaticoside has a bidirectional regulatory effect on inhibiting excessive fibroblast proliferation, preventing and minimizing pathological scars (such as cesarean section scars, burn scars and hypertrophic scars). What’s more, it can shorten wound healing time and improve the tensile strength of newly regenerated skin. As the key ingredient in clinical research and development, it is widely used to manufacture centella asiatica ointments, wound healing dressings, and intensive care ointments for diabetic foot ulcers or chronic pressure ulcers. 

3.In the dietary supplements and venous health sectors, it helps strengthen vascular endothelial cells, improves capillary elasticity and blood circulation via oral administration of asiaticoside. In Europe, it is widely used to treat and alleviate lower limb varicose veins and CVI, and produce compound capsules for leg oedema induced by longhaul flights.

Specifications

Advantages

1.Our asiaticoside purity consistently holds the premier benchmark across the sector via the selective multi-stage column chromatography separation coupled with recrystallization refining process, helping remove impurities including pigments such as chlorophyll and plant flavonoids. What’s more, its appearance shows a pure white to off-white crystalline powder with the help of this process.

2.As the product is free from any grassy odour, it does not adversely affect the fragrance or appearance when incorporated into cosmetic formulations.

3.The proprietary purification process optimizes crystal form and microscopic powder structure, resulting in crystal clear solutions and no crystal precipitation and no hazy turbidity when asiaticoside is dissolved in water. Fortunately, this process overcomes technical challenges in developing high-strength centella asiatica soothing repair serum, facial mist and toner.

4.In terms of aflatoxins, sulphur dioxide residues and microbial limits, as well as heavy metal standards of lead, arsenic, mercury and cadmium, our asiaticoside meets requirements and exceeds the statutory limits set by EU & California Prop 65. 

5.We supply full COA, MSDS, and TDS, backed by valid thirdparty test reports issued by FGS or Eurofins in line with overseas customers’ requirements, helping you mitigate all legal risks.     

FAQ

Q1: What’s the purity of asiaticoside? And what’s the difference between asiaticoside and conventional centella asiatica extract?

A: Conventional centella asiatica crude extract or total centella glycosides with lowpurity (10%-40%) are yellowishbrown in colour and have a strong grassy odour, which tends to cause discolouration or phase separation when used in luxury facial creams. By contrast, our asiaticoside, with the purity of≥98%, is a single active high-molecular-weight monomer via multi stage purification and separation technology, and inactive plant impurities and pigments are fully removed, giving an off white appearance and making it entirely free from grassy odour. Most importantly, it is the global gold standard for quantitative assay for testing whether the end products possess the ability of “cellular-level repair and catalytic collagen regeneration”.

Q2: The high purity of asiaticoside is difficult to dissolve in water, so how it its the solubility and clarity of your asiaticoside in clear serums?

A: With the purity of 98% asiaticoside possesses an excellent physical water solubility via optimizing crystal form and microscopic powder structure in upstream, resulting in crystal clear solutions and no crystal precipitation and no hazy turbidity when asiaticoside is dissolved in water. Fortunately, this process overcomes technical challenges for overseas formulators in developing high-strength centella asiatica soothing repair serum, facial mist and toner.

Q3: What’s the core pharmacological mechanism of asiaticoside in skin repair and anti-aging products?

A: It can trigger fibroblasts and penetrate deep into the dermis to boost endogenous synthesis of.type I and type III collagen, and it can rebuild reticular layer of dermis, providing the firming, wrinkle reduction and anti-ageing benefits. Besides, reducing the expression of inflammatory cytokines alleviates skin redness and stinging induced by post-aesthetic surgery or seasonal skin sensitivity. In addition, it accelerates migration of epidermal basal cells to boost wound healing, and it also  bidirectionally regulates fibroblast proliferation to prevent and minimize pathological scars and fresh red acne marks.

Q4: What’s the TECA mentioned by EU clients? And what’s the relationship between your product and TECA? 

A: TECA（Titrated Extract of Centella Asiatica) is a famous standardized compound specification, including asiaticoside, asiatic acid and madecassic acid with a fixed proportion in the European dermocosmetics sector.