Calcium Alpha Ketoglutarate
CAS 402726-78-7

Applications

1.In the field of dietary supplements, calcium alpha ketoglutarate is a favored active compound in dietary supplements for anti-aging and extended healthy lifespan, and manufacturers frequently process it into capsules and tablets. It delivers multiple practical effects: delaying biological aging, blocking glycation reactions, relieving cell-level fatigue, and improving sleep quality for middle-aged and senior consumers.

2.In the field of sports nutrition, calcium alpha ketoglutarate is used in professional sports supplements as a booster for the tricarboxylic acid cycle; it is primarily designed to rapidly produce ATP (the cell’s energy currency), enhance aerobic endurance, prevent muscle wasting (sarcopenia), and accelerate post-workout recovery following high-intensity training.

3.In bone and joint health, thanks to the synergistic interplay between calcium and AKG, calcium alpha ketoglutarate delivers efficient calcium replenishment to sustain bone mineral density. It also boosts the body’s natural collagen production, fends off osteoporosis, and provides all-round joint protection.

Specifications

Advantages

1. We apply precision crystallization control to refine calcium alpha ketoglutarate’s molecular packing and yield the optimal stable polymorph. The resulting powder boasts outstanding flowability and moisture resistance.

2.Our fully automated synthesis process enables precise molecular-level coordination between calcium ions and α-ketoglutarate, delivering a final product purity of ≥98%. The ratio of free calcium to bound calcium strictly aligns with international industry standards, with the product’s theoretical calcium content stably maintained at around 19.1%. In addition, we adopt multi-stage membrane filtration technology to control residual heavy metals including lead, arsenic, mercury and cadmium below 0.1 ppm, fully meeting high-purity product specifications.

3.We adopt dedicated refining procedures to completely strip out pigment and odor impurities from raw materials. The finished powder presents a clean white appearance with no peculiar smell and consistent particle size. Mesh grades from 80 to 120 can be tailored to individual customer needs. In addition, we maintain reliable ton-level monthly output to ensure consistent and sufficient product supply for clients.

FAQ

Q1: What is the accurate ratio of calcium and AKG in your calcium alpha ketoglutarate? Why the ratio is important?
A: We produce calcium 2-oxoglutarate via an accurate molecular coordination synthesis, yielding pure monocalcium salt with HPLC-verified purity reaching 98%. Its elemental calcium content stays steady at roughly 19.1%, fully consistent with the theoretical mass proportion. This exact ratio delivers ideal synergistic stability between calcium cations and α-ketoglutaric acid. It avoids gastrointestinal irritation triggered by free acid and maximizes oral bioavailability upon consumption.

Q2: Hygroscopic caking poses the primary challenge in capsule filling. How does your product resolve this problem?
A: We employ proprietary crystallization control technology to optimize crystal morphology and particle size distribution.Our powder boasts excellent flow properties and strong anti-hygroscopic performance. With these characteristics, your high-speed capsule filling and tableting equipment can operate continuously without downtime caused by material clogging.

Q3: What are the major global market applications of calcium alpha ketoglutarate and their corresponding scientific rationales?

A: Calcium Alpha Ketoglutarate is a key raw material for premium health applications. Its main application scenarios and supporting scientific rationales are as follows:
Premium longevity and anti-aging dietary supplements: Based on authoritative preclinical longevity studies from the Buck Institute, it delays biological aging, reverses DNA methylation markers, and restores youthful metabolic functionand promotes a youthful metabolic profile.

Q4: Does your calcium calcium alpha ketoglutarate comply with relevant regulations for dietary supplements in Europe and the United States?
A: Our company is a compliance-driven manufacturer with over ten years of international export experience. Our production lines operate in strict accordance with standardized quality management systems. We can provide a complete technical documentation package for every batch of products, which includes TDS, MSDS and batch-by-batch Certificate of Analysis (COA). We implement rigorous multi-stage impurity screening protocols that strictly controls heavy metals including lead, arsenic, mercury and cadmium to levels below 0.1 ppm., enabling our clients’ quality assurance/quality control (QA/QC) systems to smoothly pass regulatory audits in the United States, the European Union and Japan.