Epigallocatechin Gallate
CAS 989-51-5

Applications

1.In the functional skincare sector, epigallocatechin gallate (EGCG) inhibits 5α-reductase that causes overactive sebum secretion, enlarged pores and acne formation in skin. Therefore, it becomes the key ingredient in premium oil-control serum and lotion and anti-acne serum and lotion. Besides, it helps improve periorbital microcirculation and constrict dilated capillaries. For example, the most famous case is “The Ordinary 5% Caffeine + EGCG Eye Serum”, which helps improvevascular dark circles and alleviating puffiness. In addition, it alleviates skin inflammation and inhibits collagen degradation caused by UV rays, and as a result, it is widely used in after-sun repair, anti-sensitivity and anti-redness products.

2.In the dietary supplement and weight management field, epigallocatechin gallate (EGCG) plays an essential role in it. In other words, it helps inhibit the the breakdown of norepinephrine by suppressing COMT in the human body, elevating basal metabolic rate and boosting fat oxidation. Epigallocatechin gallate (EGCG), a potent antioxidant, slows aging as well as inhibiting the formation of AGEs, thereby serving as a common ingredient in oral anti-glycation formulations. 

3.In functional food and new beverage sector, epigallocatechin gallate (EGCG) is used in premium fats & oil, meat products and baked foods instead of traditional synthesis of chemical preservatives, such as BHT, BHA, inhibiting oxidative deterioration of foods. What’s more, as a key active factor, epigallocatechin gallate (EGCG) is incorporated into premium sugar-free tea drinks, sports energy drinks or anti age functional shots, serving as a mainstream high-concentration catechin raw material.

Advantages

1.We always provide monomeric epigallocatechin gallate (EGCG) refined via multistage column chromatography and recrystallization technology, which is a pure white to offwhite powder with the purity of ≥98%. 

2.Conventional green tea extract has high-concentration caffeine, oral consumption may lead to palpitations and insomnia; and topical application may irritate the skin. With our proprietary production technology, the product has virtually undetected caffeine, ensuring raw materials is mild and non-irritating as well as safe for oral consumption in fat loss and anti-ageing dietary supplements. 

3.Since epigallocatechin gallate (EGCG) is prone to discoloration upon exposure to light and oxygen, we not only supply high-purity monomeric powder, but also provide compound anti-discoloration application solutions for clients. Besides, in order to solve the challenge, we offer microencapsulated and liposomal encapsulated epigallocatechin gallate (EGCG).

4.In international logistics, we have strict controlling of nonhazardous identification, commodity inspection and customs compliance. Whether it’s the 1kg lab sample or ton-scale commercial bulk, we can arrange prompt supply.

FAQ

Q1：What’s the purity of epigallocatechin gallate (EGCG)? And what’s the difference between the two items?

A: Conventional green tea extract (Tea Polyphenol), a yellowish-brown mixture, is combined with various catechins, caffeine and pigment. When its active ingredients are diluted, it prone to skin irritation and formula discoloration. By contrast, our epigallocatechin gallate (EGCG) with the purity of ≥98% is refined via multi stage column chromatography separation technology (MCC), which thoroughly removes all impurities. In other words, its free radical scavenging capacity is several times higher than that of conventional tea polyphenol, delivering excellent performances on premium anti aging and oil control skincare products.

Q2: Numerous green tea extract has high-concentration caffeine, does your epigallocatechin gallate (EGCG) contain caffeine?

A: Our ≥98% purity epigallocatechin gallate (EGCG) makes the caffeine concentration remain at ≤0.1% via cutting-edge specific adsorption decaffeination technology (In the HPLC test, it is nearly undetectable). The “decaffeinated” standard not only ensures the mild and non-irritation ingredients for skincare products, but also enables application in “night repair” or palpitation-safe dietary supplements.

Q3: Epigallocatechin gallate (EGCG) is prone to oxidative reddening in water, how can we solve the problem?

A: We recommend that the pH value should be in a weakly acidic condition (pH 3.5-5.5), with appropriate amounts of chelating agents (EDTA-2Na) and antioxidant synergists (vitamin C derivatives or ferulic acid), which strengthens the colorful stability of epigallocatechin gallate (EGCG). Milky-white creams and clear serums have a higher requirement for stability, so we offer microencapsulated and liposomal encapsulated epigallocatechin gallate (EGCG). These formulations shield from air and light via microscopic coating, fundamentally eliminating discoloration risks and boosting skin penetration efficiency. 

Q4: In the weight management and dietary supplements sector, what’s the mechanism of action of epigallocatechin gallate (EGCG)?

A: It prevents your body to degrade COMT, thereby sustaining high levels of norepinephrine in the human body. The norepinephrine triggers signaling cascades in adipocytes to raise basal metabolic rate and fat oxidation efficiency. In addition, epigallocatechin gallate (EGCG) inhibits formation AGEs formation, improving insulin sensitivity while combating ageing at the cellular level.