Melatonin
CAS 73-31-4

Applications

1.In the field of sleep support and dietary supplements, it is widely applied to fast melt tablets, sleep gummies, sleep-support capsules and oral sleep sprays, making it the core market with the largest output value and widest application scope for melatonin. In addition, when incorporated into the above products, it shortens sleep onset latency, eases jet lag, alleviates circadian disruptions caused by shift work, and replenishes endogenous melatonin levels that drop sharply with age among middle-aged and elderly people.

2.In the field of cosmetics and anti-aging skincare, melatonin, a highly lipophilic endogenous antioxidant, easily penetrates the skin barrier. In topical skincare, it is widely used to deliver restorative effects during skin’s nightly golden repair window, neutralize free radicals triggered by UV exposure, and activate the skin’s inherent antioxidant defense system, which alleviates sagging and wrinkles induced by photoaging.

3.In the field of pharmaceuticals and clinical health, melatonin, as a high-purity pharmaceutical-grade raw material, is developed into therapeutic formulations for prescription-grade severe sleep disorders such as refractory insomnia. In addition, because it possesses immunomodulatory effects and neuroprotective activity on neuronal mitochondria, it is widely used to provide adjuvant support for mitigating neurodegenerative conditions, and is widely used as an active ingredient for foods for special medical purposes.

Specifications

Advantages

1.Produced by fully automatic closed-loop precision synthesis and multistage heterogeneous recrystallization process, the purity of melatonin remains at 99% as determined by HPLC. We adopt the most sensitive detection method, ensuring that Peak E and its related isomeric impurities are fully reduced to undetectable levels.

2.We possess an advanced production line for air-flow micronization, providing ultrafine powders with particle sizes of 80 mesh, 200 mesh, or even over 300 mesh according to clients’ requirements.

3.Full traceability management is implemented throughout the whole production process from starting materials to final crystallization and packaging. In addition, the product is 100% vegan (non-animal derived), preventing risk of cross-contamination with animal-derived materials. It is worth noting that we possess a complete Kosher, Halal and heavy metal control report that fully meets cosmetic-grade requirements (Lead, Arsenic, Mercury ＜0.1 ppm).

4.Melatonin is a premium pure white powder, appearing as fine crystalline powder under microscopic observation.

FAQ

Q1: What is the purity of your melatonin? How do you ensure it contains no hazardous impurities of Peak E?
A: Produced by fully automatic closed-loop precision synthesis and multistage heterogeneous recrystallization process, the purity of melatonin remains at ≧99% as determined by HPLC. In the global sleep supplements industry, if purification fails to meet specifications, Peak E will remain as residues. This impurity had caused a serious healthy incident. In addition, we adopt multistage heterogeneous recrystallization process to ensure that Peak E and its related isomeric impurities are fully reduced to undetectable levels, providing 100% safety endorsement for your brand.

Q2: Conventional melatonin has synthetic chemical odor, what are your product characteristics regarding color and odor?
A: Unlike market-average materials that often carry, these products exhibits pale yellow or off-white discoloration with pungent chemical odors of plastic or sour acid due to residual solvents. In contrast, our melatonin is flawless pure white crystalline powder and completely odor-free. The reason is that we adopt an aqueous washing and purification recrystallization process using pure water, which removes all volatile organic impurities, ensuring no negative impact on the color, clarity and flavor characteristics of your high-end formulas.

Q3: We are producing sleep gummies and sleep-aid liquids, do you offer any specific mesh size to prevent machine clogging and material sedimentation during production?
A: Conventional 80-mesh powder is suitable for capsule filling, but it causes severe caking and sedimentation in gummies and oral sprays. Therefore, we provide premium 200-300 mesh micronized melatonin powder that disperses uniformly with zero sedimentation in gelatin or pectin matrix, thereby guaranteeing precise dosage in every single gummy and effectively solving nozzle clogging issues in liquid sleep sprays.

Q4: Melatonin is widely applied in overnight repair cosmetics, so why are your materials suitable for premium skincare serums?
A: Melatonin, a highly lipophilic (liposoluble) molecule, easily penetrates the skin barrier. In topical cosmetics, as a potent endogenous mitochondrial antioxidant, it plays a role of surface protective barrier. In addition, it neutralizes free radicals triggered by UV rays, upregulates the skin’s native antioxidant enzyme defense system during the skin’s prime overnight repair window, and inhibits collagen degradation. Therefore, it is the key ingredient for premium clean beauty anti-aging serums.