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NUTRITION INGREDIENTS

β-Nicotinamide Adenine Dinucleotide
CAS 53-84-9

Product Name β-Nicotinamide Adenine Dinucleotide
Other Name beta-Nicotinamide adenine dinucleotide
CAS No. 53-84-9
EINECS No. 200-184-4
Purity 95%
Molecular Formula C₂₁H₂₇N₇O₁₄P₂
Molecular Weight 663.43
Appearance White or off-white crystalline powder
Packing 1kg/5kg Aluminum foil bag
25kg/Drum
25kg/Carton
or customized as per customer's requirements
Storage Store in a cool, dry place, tightly sealed, away from heat and light
MOQ 1KG
Payment T/T, LC or DA
Delivery Time Ready Stock in Local Warehouse, 1-3 days
Origin China
Shipping DHL, FedEx, TNT, EMS, By Sea, By Air

Description

β-nicotinamide adenine dinucleotide is not only an important core coenzyme in the human cells, but also the ultimate active endpoint for all NAD⁺ supplements, such as NMN and NR, in the human body. In addition, it directly participates in hundreds of ATP-producing cellular energy metabolic reactions, activates sirtuins, and supports DNA damage repair, making it a vital key rate-limiting substrate.

Applications

1. In the field of IVD and biochemical assay kits, β-nicotinamide adenine dinucleotide and its L-NADH, core hydrogen-transfer coenzymes, are widely applied in routine clinical biochemical tests covering liver function, cardiac enzyme and renal function panels, such as LDH, ALT and AST assay kits.

2.In cellular anti-aging and premium dietary supplements, β-nicotinamide adenine dinucleotide can be taken orally, sublingually or administered via intravenous infusion (NAD⁺ IV Therapy) for clinical applications. β-nicotinamide adenine dinucleotide is readily available for cellular uptake and bypasses all bodily precursor conversion pathways. In addition, it activates the full sirtuin longevity family (SIRT1–7), enhances mitochondrial ATP synthesis, and facilitates PARP-driven DNA repair, thereby relieving severe chronic fatigue, preventing precipitous declines in physiological function, and prolonging healthspan.

3.In the field of brain rejuvenation and neurotransmitter regulation, it optimizes synthetic pathways for neurotransmitters including dopamine and norepinephrine. Therefore, β-nicotinamide adenine dinucleotide is incorporated into premium formulations for eliminating severe brain fog, restoring long-term memory, and relieving neuronal damage caused by late nights and chronic high stress.

4.In the field of functional cosmetics and bio-grade medicated skincare, typical β-nicotinamide adenine dinucleotide penetrates directly to the epidermal basal layer, downregulates local inflammatory cytokines, and offers robust defense against collagen degradation and skin barrier collapse caused by UV photodamage.

Specifications

Parameter Specification / Requirement
Appearance White Powder
Solubility Soluble in water
ε at 260nm and pH 7.5 (18.0±1.0) × 10³ L/mole/cm
ε (reduced with ADH) at 340nm and pH 10 (6.3±0.2) × 10³ L/mole/cm
Ratio at pH 7.5
A₂₅₀/A₂₆₀ 0.83±0.03
A₂₈₀/A₂₆₀ 0.21±0.02
Ratio (reduced with ADH at pH 10)
A₃₄₀/A₂₆₀ 0.43±0.01
Water (by K.F.) ≤10%
Arsenic (As) ≤1 ppm
Total Bacterial Count < 100 CFU/g
Staphylococcus aureus Negative
Moulds < 100 CFU/g
E. coli Negative
Salmonella Negative
Content ≥90%
Purity (HPLC) ≥95%

Advantages

1. Produced by a precise enzymatic catalysis and multi-stage chromatographic separation technology, the purity of β-nicotinamide adenine dinucleotide meets the highest standard in the industry. Strict testing is carried out on absorbance and impurity peaks at 340 nm to ensure bulk materials deliver ultra-high sensitivity, an extremely wide linear range and outstanding batch-to-batch stability, and satisfying the stringent QC audit standards of international pharmaceutical-grade diagnostic reagent manufacturers once formulated into liquid biochemical reagents.

2.We adopt an advanced crystallization technology with low-temperature water control and customized drying process in the production line, making the end crystal particles feature a denser surface, with a moisture absorption rate markedly lower than the industry average.

3.Our product is synthesized by full enzymatic process, simulating the natural biotransformation pathways inside cells. Our specifications for heavy metals (lead, arsenic, mercury, cadmium), microbial limits and aflatoxins surpass the regulatory requirements set by EFSA and the U.S. FDA. Whether for oral administration or IV infusion in premium clinics, the product is absolutely safety.

4.We adopt the top-grade moisture-proof and light-shielding dual-layer food-grade inner bags paired with high-density vacuum-sealed aluminum foil bags, filled with high-efficiency desiccants inside; externally packed in sturdy temperature-controlled cold-chain fiber drums. In addition, we can handle cross-border non-dangerous goods declaration and expedited air customs clearance, ensuring 1–5 kg sample orders facilitate smooth customs clearance.

FAQ

Q1: What is the purity of your β-nicotinamide adenine dinucleotide ? Does it comply with rigorous standards for clinical chemistry IVD reagent kits?
A: The purity of β-nicotinamide adenine dinucleotide, a pure white powder, is ≥98% as determined by HPLC. Regarding rigorous standards for clinical chemistry IVD reagent kits, the product’s absorbance and background noise at 340nm are optimized. Therefore, it guarantees bulk goods features ultra-high sensitivity, an extremely wide linear range, excellent batch-to-batch stability, and meets the stringent QC audit requirements of international pharmaceutical-grade diagnostic reagent manufacturers after formulating into liquid biochemical reagents.

Q2: β-nicotinamide adenine dinucleotide easily takes up moisture and leads to hydrolytic degradation. What advantages does this material have in physical stability and crystal morphology?
A: Produced by an advanced low-temperature water-controlled crystallization and proprietary drying process, crystal structure of the powder is optimized. In addition, the crystal particles feature a denser surface, with a moisture absorption rate markedly lower than the industry average. Therefore, it ensures that materials do not adhere to equipment walls and resist loss of activity, extending the shelf life of end products in fully automatic high-speed dispensing, capsule filling, and cosmetic emulsification production processes.

Q3: Which process do you adopt? How do you ensure the material is free from inactive isomers and chemical residues?
A: We adopt a 100% eco-friendly, bio-enzymatic catalytic process. In the whole process, the catalytic and purification pathways fully mimic the natural biotransformation processes inside human cells. In addition, we only use purified water and highly specific biological enzymes, and do not add any toxic chemical reagents or industrial solvents, which ensures zero inactive optical isomers and residual chemicals. Tested by independent third parties (such as SGS / Eurofins), heavy metals (lead, arsenic, mercury, cadmium), microbial limits and aflatoxins surpass the regulatory requirements set by EFSA and the U.S. FDA. Whether for oral administration or IV infusion in premium clinics, the product is absolutely safe.

Q4: Why is β-nicotinamide adenine dinucleotide the best choice for premium anti-aging dietary supplements?
A: Unlike NMN and NR-Cl, which must undergo a complex cascade of enzymatic reactions to convert into active NAD⁺ before taking effect, β-nicotinamide adenine dinucleotide skips those multi-step conversions and acts on the human body directly to deliver its physiological benefits. High-purity β-NAD⁺ is inherently the fully bioactive molecule that works instantly without extra transformation. Sold globally for both oral supplementation and intravenous administration at premium medical clinics, it eliminates conversion loss entirely: it energizes mitochondria, repairs DNA damage, and rapidly relieves cellular weariness at the cellular level.

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